Eigen Insights / ORIGIN

From biological questions to testable hypotheses.

Automated bioinformatics and biological reasoning in one research workspace.

Connect molecular data with mechanistic evidence. Review the analysis, trace the rationale, and decide what to test next.

ORIGIN workflow film
Silent looping film

A research question becomes an analysis, a biological network, and an evidence-linked rationale for scientific review.

Read the film description
  1. Question. RNA data and study context frame a research question.
  2. Analysis. Schematic graphs represent scoped bioinformatics analysis.
  3. Network. Molecular relationships and supporting evidence connect findings to biological hypotheses.
  4. Rationale. Methods, evidence, uncertainty, and open questions inform a research brief and a next-step validation plan.

The visual is illustrative. Project scope and scientific review determine the analysis and deliverables.

For biopharma & research organizations

Investigate mechanisms
with molecular context.

Begin with a specific research question and a defined deliverable.

Automated bioinformatics organizes computational work around the available data. Biological reasoning connects the findings to regulatory programs, molecular relationships, and mechanistic evidence. Scientific review shapes the interpretation and validation plan.

Deployment, data access, retention, and permitted use are agreed for the engagement. Dedicated environments can be scoped around a partner’s security and governance requirements.

Explore the scientific platform

Engagement process

Scope an ORIGIN evaluation.

01

Define the question

Align on a disease state, research decision, and criteria for a useful outcome.

02

Scope the evidence

Review data availability, quality, permissions, and the appropriate deployment environment.

03

Investigate the biology

Connect model outputs with mechanistic evidence and scientific interpretation.

04

Review and validate

Examine findings, uncertainties, and experiments needed before the next development decision.

Example research scopes

Questions ORIGIN
can help investigate.

Illustrative project scopes. Deliverables are agreed for each engagement.

  • Mechanism and resistanceInvestigate regulatory programs associated with a response or persistent disease state.
  • Biomarkers and patient groupsExamine candidate molecular signatures and define how they should be tested.
  • Target and indication hypothesesConnect disease biology with opportunities for further qualification and validation.
  • Failure analysisRevisit a program’s biological assumptions using available molecular and experimental evidence.

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Evaluate ORIGIN with your team.

Tell Eigen Insights about your research decision, available evidence, and working environment.

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